Look up this 2008 paper from the Wuhan Institute of Virology with a Google search for “Difference in receptor usage between severe acute respiratory syndrome (SARS) coronavirus and SARS-like coronavirus of bat origin.”
“In this study, we investigated the receptor usage of the SL-CoV S by combining a human immunodeficiency virus-based pseudovirus system with cell lines expressing the ACE2 molecules of human, civet, or horseshoe bat.”
Can Virologists translate that to ‘we stuck some segments of HIV into a Coronavirus to see what would happen?’
From the paper:
“First, the SL-CoV S was unable to use any of the three ACE2 molecules as its receptor. Second, the SARS-CoV S failed to enter cells expressing the bat ACE2. Third, the chimeric S covering the previously defined receptor-binding domain gained its ability to enter cells via human ACE2, albeit with different efficiencies for different constructs. Fourth, a minimal insert region (amino acids 310 to 518) was found to be sufficient to convert the SL-CoV S from non-ACE2 binding to human ACE2 binding, indicating that the SL-CoV S is largely compatible with SARS-CoV S protein both in structure and in function.”
This basically states that the SARS-Like Coronavirus (a different virus than the SARS virus strain from the early 2000’s outbreak) they had found in bats was not transmissable to humans due to it not binding to the ACE2 receptor, but that with a minimal insertion of genome from HIV it was able to bind to human ACE2 receptor and not just the bat receptors.
This may be a seperate SARS-Like coronavirus from what we’re seeing right now, but the takeaway is this: first, that the strain from bats was not directly transmissable to human beings; and secondly, that the wuhan institute of virology was able to engineer a human transmissable strain with insertion of HIV DNA across only a small portion of the SL-CoV S.
It also shows that the human SARS Coronavirus (responsible for the SARS outbreak in china more than a decade ago) is not transmissable to bats. This means that the SARS-Like Coronavirus they originally found in bats – and subsequently experimented with – is a seperate but probably related disease.
That’s only within the first few paragraphs. There is a lot more digging to do. When I checked google scholar for papers there were several dozens of CoV papers all generated in china, and most were concerned with bats being the natural resevoirs for the virus and the mechanics of transmission within humans.
That itself is not conspiratorial, the virus does only occur within bats naturally and the 2002-2003 SARS outbreak in china likely originated within a bat population which then transmitted the virus to an intermediary animal before it infected humans. Due to only that fact it is entirely natural to investigate every CoV strain in bats, and the possibility of human transmission.
What is spooky is that it was so easy to engineer such a strain, and that they used HIV for creating the chimera virus.